Last word on point: skeletal muscle mechanical efficiency does increase with age.

Point : Counterpoint 1 2 “ Skeletal muscle mechanical efficiency does / does not increase

Point:Counterpoint: Skeletal muscle mechanical efficiency does/does not increase with age POINT: SKELETAL MUSCLE MECHANICAL EFFICIENCY DOES INCREASE WITH AGE

We thank Dr. Ortega for the opportunity to debate the concept that aging affects exercise efficiency. From the outset we must acknowledge that, indeed, some studies report an age-related reduction task efficiency during walking and other rather complex tasks (2, 12, 20, 21). However, in contrast, our recent study of leg cycling in centenarians (28), as well as other work focused more specifical...

Comments on point:counterpoint: skeletal muscle mechanical efficiency does/does not increase with age.

TO THE EDITOR: There is little doubt that the cost of locomotion is impaired with age as it is evident that centenarians, due to their exceptional longevity, present unique adaptations in their skeletal muscle efficiency to compensate for their extremely low V̇O2max. However, the underlying question of whether skeletal muscle efficiency is altered with age is unsettled (4, 6). In fact, both oppo...

Point: skeletal muscle mechanical efficiency does increase with age.

We thank Dr. Ortega for the opportunity to debate the concept that aging affects exercise efficiency. From the outset we must acknowledge that, indeed, some studies report an age-related reduction task efficiency during walking and other rather complex tasks (2, 12, 20, 21). However, in contrast, our recent study of leg cycling in centenarians (28), as well as other work focused more specifical...

Effects of ionic parameters on behavior of a skeletal muscle fiber model

All living cells have a membrane which separates inside the cell from it's outside. There is a potential difference between inside and outside of the cell. This potential difference will change during an action potential. It is quite common to peruse action potentials of skeletal muscle fibers with the Hodgkin-Huxley model. Since Hodgkin and Huxley summarized some controlling currents like inwa...